The Mechanism of Action of Androgens

The Mechanism of Action of Androgens

Author: W.I.P. Mainwaring

Publisher: Springer Science & Business Media

ISBN: 9783642884290

Category: Medical

Page: 180

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My introduction to androgens was neither auspicious nor impressive. I was sitting my viva voce examination for a degree in physiology and had haltingly intimated to my examiner (name decorously withheld) that I intended to pursue a career in re search. "On what topic?" was the reply. I had been deeply impressed by the work of C. Huggins and C. V. Hodges (Cancer Res. 1, 293, 1941) on the dramatic arrest of canine prostatic hyperplasia by the administration of stilboestrol. With some en thusiasm, I responded, "On steroid hormones, because I am struck by the profound effects that may be achieved by relatively small numbers of molecules. " The examiner sank into deep contemplation before replying, "Young man, have you considered go ing into teaching?" Suitably chastened, I finally began my research career investigating the effects of steroids on the nucleic acid metabolism of experimental tumours and on the process cells. Reaching an impasse in this work, I mentioned one of senescence in animal day to Dr. G. F. Marrian that, somewhat surprisingly, we had no understanding of the fundamental mechanism of action of steroid hormones, especially the androgens. me to tackle this problem, particularly since exciting new insights He encouraged were then being made into the interaction of radioactively labelled oestradiol-l?,8 with such tissues as rat uterus.
The Mechanism of Action of Androgens
Language: en
Pages: 180
Authors: W.I.P. Mainwaring
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

My introduction to androgens was neither auspicious nor impressive. I was sitting my viva voce examination for a degree in physiology and had haltingly intimated to my examiner (name decorously withheld) that I intended to pursue a career in re search. "On what topic?" was the reply. I had been
Role of RNA Synthesis in the Mechanism of Androgen Action
Language: en
Pages: 156
Authors: Anja Kuosa
Categories: Androgens
Type: BOOK - Published: 1983 - Publisher:

Books about Role of RNA Synthesis in the Mechanism of Androgen Action
Schering Symposium on Biodynamics and Mechanism of Action of Steroid Hormones, Berlin, March 14 to 16, 1968
Language: en
Pages: 364
Authors: Gerhard Raspé
Categories: Science
Type: BOOK - Published: 2013-10-22 - Publisher: Elsevier

Advances in Biosciences 2 documents the proceedings of the Schering Symposium on Biodynamics and Mechanism of Action of Steroid Hormones held in Berlin, on 14-16 March 1968. The volume begins by presenting the opening address on the symposium's main themes followed by a lecture on the factors influencing the nature
Hirsutism
Language: en
Pages: 112
Authors: P. Mauvais-Jarvis, F. Kuttenn, I. Mowszowicz
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

In the past 10 years hirsutism has been the object of a considerable number of fundamental studies. It provides endocrinologists with an experimental model for the investigation of androgen secretion, metabolism and mechanism of action. Plasma androgen assay, free testosterone measurement, hepatic and extrahepatic androgen metabolic clearance and androgen metabolism
Mechanism of Action of Anabolic-androgenic Steroids
Language: en
Pages: 360
Authors: Amy B. Cadwallader
Categories: Anabolic steroids
Type: BOOK - Published: 2008 - Publisher:

Books about Mechanism of Action of Anabolic-androgenic Steroids